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HeartSine 350P vs 360P vs 450P — the three-way Pad-Pak lineup

HeartSine 350P vs 360P vs 450P — the three-way Pad-Pak lineup

AED Best Brands Editorial Team

Independent AED research desk

Updated July 3, 2026
HeartSine 350P vs 360P vs 450P — the three-way Pad-Pak lineup | AED Best Brands

HeartSine markets three AEDs in the Samaritan PAD line: the 350P (semi-automatic), 360P (fully automatic), and 450P (semi-automatic with CPR rate advisor). All three share the same lightweight 2.4 lb chassis, the same IP56 outdoor rating, the same 4-year combined Pad-Pak architecture, and the same 10-year device warranty. What differs is shock-delivery automation and CPR coaching.

Buyers usually arrive at this comparison after deciding HeartSine is the right brand — the lineup question is which configuration matches their operating environment. The price gap from cheapest to most expensive is roughly $500 ($995 to $1,495).

Quick answer

350P for single-AED budget buyers, schools, churches, and small businesses with trained or partially trained responders. 360P for fully-public-access deployments where the rescuer may be untrained — fully automatic eliminates shock-button hesitation. 450P for facilities with designated responders who want CPR rate coaching but not necessarily full Real CPR Help® depth measurement.

Head-to-head three-way spec comparison

Spec 350P 360P 450P
Retail price (2026) $995 $1,195 $1,595
Shock delivery Semi-automatic Fully automatic Semi-automatic
CPR feedback Voice prompts only Voice prompts only CPR rate advisor (visual)
Pad-Pak shelf life 4 years 4 years 4 years
Pad-Pak cost ~$120 ~$130 ~$170
Pediatric workflow Separate Pediatric Pad-Pak Auto-detect Separate Pediatric Pad-Pak
IP rating IP56 IP56 IP56
Weight 2.4 lb / 1.1 kg 2.4 lb / 1.1 kg 2.4 lb / 1.1 kg
Warranty 10 years 10 years 10 years
5-year total ownership cost $1,215–$1,500 $1,420–$1,700 $1,720–$2,100

The 350P — lowest 5-year cost on the market

The HeartSine 350P at $995 retail is the cheapest FDA-cleared AED in the US market. With one $120 Pad-Pak replacement over 5 years and a $149 cabinet, the program totals $1,264 over 5 years — the lowest in the AED comparison set. The 2026 AED Best Brands Best Budget award sits on this device.

The trade-offs: semi-automatic only (shock-button hesitation risk in untrained rescuers), voice prompts only (no CPR coaching), and a separate Pediatric Pad-Pak required for child rescue. For schools and small businesses with trained or partially-trained responders, those trade-offs are acceptable. For lay-public-access deployments, they are not.

The 360P — fully automatic plus auto-detect pediatric

The 360P is the only HeartSine device with fully automatic shock delivery. Combined with auto-detect pediatric (no separate Pad-Pak required for child rescue), the 360P is the lay-public-access pick in the HeartSine lineup.

The auto-detect feature works through the Pad-Pak’s built-in sensors — the device estimates patient size from pad impedance and adjusts shock energy accordingly. This is not as clean as the LIFEPAK CR2’s button-based child mode or the FRx’s Infant/Child Key, but for facilities that prefer one-pad-set simplicity, the 360P removes the swap workflow.

The 450P — CPR rate advisor adds coaching

The 450P adds a visual CPR rate advisor — a flashing icon that shows the rescuer the target compression rate (100-120 BPM per AHA guidelines). This is rate coaching only, not depth coaching. ZOLL devices provide both depth + rate coaching; HeartSine’s 450P provides rate only.

For facilities with designated responders who want some CPR coaching but not the premium ZOLL price, the 450P is a middle option. Trade-off: $300 premium over the 350P for what is genuinely a less comprehensive coaching feature than what ZOLL offers.

Pad-Pak economics across the lineup

All three devices use the same Pad-Pak architecture: a single combined cartridge that includes both the electrode pads and the battery, with a 4-year shelf life. Buyers track one expiration date for the consumables. Replacement is one purchase every 4 years.

The Pad-Pak cost differs slightly across the three devices — 350P at $120, 360P at $130, 450P at $170 — reflecting the additional sensors in the higher-tier units. Pediatric Pad-Pak costs roughly $170 across all three.

Real-world deployment scenarios

Scenario A — small Baptist church, 250 members, single deacon trained in CPR

Budget-conscious. Adult congregation. One trained responder. Recommendation: HeartSine 350P. $995 retail. The deacon’s training covers semi-automatic shock-button workflow. No pediatric requirement (no childcare program). 5-year total ~$1,264 — fits a small church budget.

Scenario B — community recreation center, lobby AED, untrained volunteer staff

Public access. Volunteer-staffed front desk. High turnover. Mixed adult + occasional child program. Recommendation: HeartSine 360P. Fully automatic removes shock-button hesitation. Auto-detect pediatric covers occasional child use. IP56 supports an outdoor pool deck if expanded.

Scenario C — 80-employee manufacturing shop, 1 AED, on-staff safety manager certified in CPR

Trained responder. Industrial floor environment. The safety manager wants CPR coaching but not full ZOLL premium. Recommendation: HeartSine 450P. CPR rate advisor + IP56 dust-and-water rating + lightweight 2.4 lb chassis match a shop-floor wall-mount deployment.

Verdict by buyer profile

Budget-First · Schools · Churches · Small Business

HeartSine 350P

Cheapest FDA-cleared AED on the market. The 5-year program totals roughly $1,264. The pick when low cost + low maintenance overhead are non-negotiable. Read 350P review →

Lay Public Access · Untrained Staff · Mixed-Age

HeartSine 360P

Fully automatic removes shock-button hesitation. Auto-detect pediatric handles occasional child rescue. The lay-public-access pick in the HeartSine lineup. Read 360P review →

Designated Responder · Wants CPR Coaching · Light + Rugged

HeartSine 450P

CPR rate advisor + IP56 + 10-year warranty. The pick when the operating environment wants some coaching at a sub-ZOLL price. Read 450P review →

Frequently asked questions

Are all three FDA-cleared?

Yes. All three hold current 510(k) clearance. Verify in the FDA database before purchase.

Which has the lowest 5-year cost?

The 350P at roughly $1,264 over 5 years, including one Pad-Pak replacement and a cabinet.

Are the Pad-Paks interchangeable across the three models?

No. Each model uses a model-specific Pad-Pak (different sensors in the 450P and 360P). Buy the correct Pad-Pak for the device.

Which one is the lightest?

All three weigh 2.4 lb / 1.1 kg — the lightest FDA-cleared AED chassis on the market.

Does the 450P provide depth-of-compression coaching?

No. The 450P provides rate coaching only (visual icon showing target BPM). For depth + rate coaching, the ZOLL AED Plus or ZOLL AED 3 is the correct pick.

Which is the right choice for outdoor sports fields?

The 360P (fully automatic) for lay-rescuer environments, or the 450P (with CPR coaching) for designated-responder programs. All three carry IP56, suitable for outdoor deployment with cabinet protection.

Run the math for your specific facility

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Sources

  1. FDA 510(k) database
  2. American Heart Association — CPR + AED guidance
  3. HeartSine (Stryker) — Samaritan PAD 350P, 360P, 450P product specifications

Educational comparison. Pricing reflects 2026 authorized US distributor reference points.

In this guide

Contextual pick · One date
Heartsine Samaritan PAD 450P Products
HeartSine 450P

Pads + battery in one 4-year cartridge, ~$169. The maintenance plan that survives turnover.

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References · primary sources

  1. ClinicalAmerican Heart Association. CPR Facts and Stats. cpr.heart.org facts
  2. ProgramAmerican Heart Association. Implementing an AED Program, 2023 guide (placement, pediatric guidance, readiness). cpr.heart.org AED guide (PDF)
  3. RegulatoryUS FDA. Automated External Defibrillators and Premarket Approval database. fda.gov AEDs
  4. ManufacturerZOLL Medical. AED Plus and AED 3 product and consumables documentation. zoll.com AEDs
  5. ManufacturerPhilips. HeartStart OnSite and FRx support, pads and battery IFU. philips.com emergency care
  6. ManufacturerStryker. HeartSine Samaritan PAD and Pad-Pak documentation. stryker.com emergency care
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